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The genesis of cancer : a study in the history of ideas / L.J. Rather.


Baltimore : Johns Hopkins University Press, [1978] .
ISBN 0801821037, 9780801821035

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Subjects Cancer -- Histoire.
Cancer -- History.
Cancer.
Carcinogenese.
Neoplasms -- History.
Theorieën.
Description xiii, 262 pages ; 24 cm
Copyright Date [1978]
©1978
Notes Includes bibliographical references (pages 231-248) and index.
Summary Here the phrase 'tumor genesis' refers chiefly to the material and formal genesis of tumors; their etiology, or causal genesis, is not an issue. The questions are, from what component of the body, whether fluid or solid, are tumors derived, and what are the factors determinative of their gross and microscopic structure? This book is an attempt to show that a thread of logical continuity runs through the long history of Western medical thought on the genesis of tumors. In the first chapter, changing ideas of the genesis of tumors during the past two thousand years of the Western medical tradition are reviewed. The second chapter gives an account of the development of knowledge of the fine structure of animal bodies which culminated in the rise of tissue theory at the end of the eighteenth century and its application to the problem of tumor genesis in the beginning of the nineteenth century. The third chapter is devoted to the study of the structure and genesis of tumors in the light of Schwannian cell theory in Germany in the 1840s and the fourth chapter details the overthrow of Virchow's concept of the connective-tissue genesis of epithelial cancer some twenty years later. The fourth chapter does not carry the story past the 1880s because the presuppositions underlying the inferences drawn from this cumulative evidence underwent little significant change during the subsequent seventy to eighty years. Only in very recent times have techniques been introduced that shed new light on the genesis of tumors. -- from Preface and Introduction.
Contents 1. Tumors and the development of humoral theory, fifth century B.C. to 1800: -- Paleopathology of animal tumors -- Tumor theory -- Movement of the blood -- Iatrochemical humoralism -- Lymph; -- 2. Tumors and tissue theory, fifth century B.C. to 1838: -- Anatomical science -- Tissue theory -- Tissues and tumors -- English and scotch investigators -- Germ-layer theory; -- 3. Cell theory and the genesis of cells in tumors, 1852-1900: Use of the microscope -- Schwann's papers of 1838 and their reception by Mueller -- Revision of mueller's theory -- Tissues redefined in the light of Schwann's cell theory -- Cell theory: genesis of cells in tumors -- Debates over the specificity of cancer cells; -- 4. Cell theory and the genesis of cells in tumors, 1852-1900: -- Blastema theory -- Foerster and the new cellular pathology -- Virchow and the new cellular pathology -- Michel's criticism of Virchow's connective tissue theory -- Limits of cell specificity -- Molecular biology foreshadowed.
Genre History.
Network Numbers (OCoLC)3707901
(OCoLC)ocm03707901
WorldCat Search OCLC WorldCat
WorldCat Identities Rather, L. J.
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